Cissus quandragularis: injury and weight-loss aid?

Cissus quandragularis has been used for years in Ayuverdic practices and has been studied for its several properties. This part of the grape family contains alkaloids, saponins, tannins, flavonoids, glycosides and has a high mineral content, with the absence of toxic substances.

Anti-inflammatory

A study conducted on rats showed anti-inflammatory and antipyretic activity within 1 to 5 hours. (Still, it's a rat study)

Anti-microbial

In 2004, a study showed anti-microbial activity of Cissus Q. extracts against certain Gram-positive bacteria such as Bacillus subtilisBacillus cereusStaphylococcus aureus, and Streptococcus species.

Fracture Healing

A study published in 1994 in the Indian Journal of Pharmacology, showed significant fracture healing in dogs. The study revealed that the Cissus (CQ) group (in contrast to the placebo group) showed faster initiation of the healing process and complete healing. (Who let the dogs out? CQ! CQ! CQ!)

Anti-osteoporotic properties were shown to exist in a study conducted in rats, significant even when compared with the commonly used drug raloxifene. (Keep in mind, the study was conducted in rats, so we do need human studies in order to evaluate the healing potential)

Weight loss

In a study conducted in 123 obese and overweight individuals in 2006, results showed a promising edge for CQ. To quote the researchers: "At the end of the trial period, statistically significant net reductions in weight and central obesity, as well as in fasting blood glucose, total cholesterol, LDL-cholesterol, triglycerides, and C-reactive protein were observed in participants who received the formulation, regardless of diet." (note: C-reactive protein is an inflammation marker, which shows again the anti-inflammatory activity of CQ)

Another study conducted in 2008 showed reduction in body weight, body fat, waist size; total plasma cholesterol, LDL cholesterol, fasting blood glucose level in the CQ group (placebo-controlled study in humans) by the end of 10 weeks.

Stay healthy!

DICLAIMER: I am not a medical doctor, nor do I act as one. Always consult your medical professional before implementing any changes to your diet and/or medication. 

References:

https://www.sciencedirect.com/science/article/pii/S0378874103003015

https://lipidworld.biomedcentral.com/articles/10.1186/1476-511X-7-12

https://lipidworld.biomedcentral.com/articles/10.1186/1476-511X-5-24

https://www.researchgate.net/profile/Dilip_Deka/publication/242131158_Effect_of_Cissus_quadrangularis_in_accelerating_healing_process_of_experimentally_fractured_radius-ulna_of_dog_A_preliminary_study/links/58ac4dc7458515040205f644/Effect-of-Cissus-quadrangularis-in-accelerating-healing-process-of-experimentally-fractured-radius-ulna-of-dog-A-preliminary-study.pdf

http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.668.5685&rep=rep1&type=pdf

http://online.liebertpub.com/doi/abs/10.1089/109662003322233495

Cover image photo source:
http://www.pitchandikulam-herbarium.org/img/plants/flower/cissus_quadrangularis_flower7.jpg